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Dexmedetomidine Hydrochloride
(CAS RN:145108-58-3 Product Number:D5062)

Structure

Dexmedetomidine Hydrochloride
Synonym (S)-4-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole Hydrochloride
Synonym (+)-Medetomidine Hydrochloride
Synonym (S)-4-(α,2,3-Trimethybenzyl)-1H-imidazole Hydrochloride

General Information

Product Number D5062

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Purity/Analysis Method >98.0%(HPLC)(T)
Storage Temperature <0°C
M.F. / M.W. C13H16N2·HCl=236.74
CAS RN 145108-58-3
Related CAS RN 113775-47-6
MDL Number MFCD12912677
Packaging and Container
  • Product Details
  • Safety & Regulations

Specification

Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Argentmetric Titration) min. 98.0 %
Melting point 156.0 to 160.0 deg-C
Specific rotation [a]20/D +49.0 to +54.0 deg(C=1, H2O)

References

Reaxys-RN 8937629
PubChem SID 354333214
Merck Index(14) 2946
RTECS# NI5156750

GHS

Pictogram
Signal Word Warning
Hazard Statements
  • H302
  • :Harmful if swallowed.
  • H315
  • :Causes skin irritation.
  • H319
  • :Causes serious eye irritation.
Precautionary Statements
  • P264
  • :Wash hands and face thoroughly after handling.
  • P270
  • :Do not eat, drink or smoke when using this product.
  • P280
  • :Wear protective gloves, eye protection.
  • P301+P312+P330
  • :IF SWALLOWED: Call a POISON CENTER or doctor if you feel unwell. Rinse mouth.
  • P302+P352+P332+P313+P362+P364
  • :IF ON SKIN: Wash with plenty of water. If skin irritation occurs: Get medical advice or attention. Take off contaminated clothing and wash it before reuse.
  • P305+P351+P338+P337+P313
  • :IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists: Get medical advice or attention.

Transport Information

HS Number 2933299090

Application

Dexmedetomidine Hydrochloride: A Potent and Selective α2-Adrenoceptor Agonist

Dexmedetomidine hydrochloride is a potent α2-adrenoceptor agonist, which produces and analgesia, about 8 times higher selective affinity for the α21-adrenoceptor than clonidine [D1353]. Dexmedetomidine also binds to imidazoline receptors, based on the imidazole group. (The product is for research purpose only.)

References

PubMed Literature

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