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Enalapril Maleate
(CAS RN:76095-16-4 Product Number:E1010)

Structure

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Enalapril Maleate
Synonym 1-[N-[(S)-1-Ethoxycarbonyl-3-phenylpropyl]-L-alanyl]-L-proline Maleate

General Information

Product Number E1010

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Purity/Analysis Method >98.0%(HPLC)(T)
Storage Temperature
M.F. / M.W. C20H28N2O5·C4H4O4=492.53
CAS RN 76095-16-4
Related CAS RN 75847-73-3
MDL Number MFCD00133304
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Specification

Purity(HPLC) min. 98.0 area%
Purity(Neutralization titration) min. 98.0 %
Specific rotation [a]20/D -40.0 to -43.0 deg(C=1, MeOH)

Data of Reference

λmax 208(MeOH)(lit.)

References

Reaxys-RN 3645274
PubChem SID 253661645
Merck Index(14) 3567
RTECS# TW3666000
EC Number 278-375-7

Transport Information

HS Number 2933998090

Application

Enalapril Maleate: An Angiotensin-Converting Enzyme Inhibitor (ACEI)

Enalapril maleate is an angiotensin-converting enzyme inhibitor (ACEI) without a mercapto group, used in the treatment of hypertension. Enalapril is a prodrug which is hydrolysed by various esterases in the host's liver to form the ACEI, enalaprilat [E1302]. Enalapril increases plasma renin activity (PRA) and decreases plasma concentrations of angiotensin II and aldosterone. (The product is for research purpose only.)

References

PubMed Literature

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