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(CAS RN:155270-99-8 Product Number:I1100)


Synonym (E)-8-(3,4-Dimethoxystyryl)-1,3-diethyl-7-methyl-1H-purine-2,6(3H,7H)-dione

General Information

Product Number I1100

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Purity/Analysis Method >98.0%(HPLC)(T)
Storage Temperature 0-10°C
M.F. / M.W. C20H24N4O4=384.44
CAS RN 155270-99-8
Related CAS RN
MDL Number MFCD00928421
Packaging and Container
  • Product Details
  • Safety & Regulations


Purity(HPLC) min. 98.0 area%
Purity(with Total Nitrogen) min. 98.0 %
Melting point 191.0 to 195.0 deg-C

Data of Reference

λmax 362(CH2Cl2)(lit.)


Reaxys-RN 7863436
RTECS# UO8414732


Signal Word Warning
Hazard Statements
  • H361fd
  • :Suspected of damaging fertility. Suspected of damaging the unborn child.
Precautionary Statements
  • P201
  • :Obtain special instructions before use.
  • P202
  • :Do not handle until all safety precautions have been read and understood.
  • P280
  • :Wear protective gloves, protective clothing, face protection.
  • P308+P313
  • :IF exposed or concerned: Get medical advice or attention.
  • P405
  • :Store locked up.
  • P501
  • :Dispose of contents/container through a waste management company authorized by the local government.

Transport Information

HS Number 2933599590


Istradefylline: A Selective Adenosine A2A Receptor Antagonist

Istradefylline (KW-6002) is a selective adenosine A2A receptor antagonist. Adenosine A2A receptors are a G protein-coupled receptor (GPCR), and also one of the receptors of adenosine. In the brain, adenosine A2A receptors are considered to be present specifically in the basal ganglia, and are thought to be involved in the regulation of motor functions. The degeneration or abnormality observed in Parkinson's disease (PD) is believed to occur in the basal ganglia. Istradefylline as a high affinity and selectivity for A2A receptors. Reportedly, istradefylline has improved motor function in patients with advanced PD including loss of L-DOPA [D0600] efficacy. (The product is for research purpose only.)


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