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N-Methyl-N-propargylbenzylamine
(CAS RN:555-57-7 Product Number:M2618)

Structure

N-Methyl-N-propargylbenzylamine
Synonym N-Methyl-N-(2-propyn-1-yl)benzylamine
Synonym Pargyline

General Information

Product Number M2618

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Purity/Analysis Method >98.0%(GC)(T)
Storage Temperature
M.F. / M.W. C11H13N=159.23
CAS RN 555-57-7
Related CAS RN
MDL Number MFCD00008576
Packaging and Container
  • Product Details
  • Safety & Regulations

Specification

Purity(GC) min. 98.0 %
Purity(Nonaqueous Titration) min. 98.0 %
Refractive index n20/D 1.5200 to 1.5240
Specific gravity (20/20) 0.9500 to 0.9540

Data of Reference

flp 84°C(lit.)
bp 90°C/4mmHg(lit.)

References

Reaxys-RN 1938132
PubChem SID 354333810
Merck Index(14) 7038
RTECS# DP6475000
EC Number 209-101-6

GHS

Pictogram
Signal Word Danger
Hazard Statements
  • H301
  • :Toxic if swallowed.
  • H315
  • :Causes skin irritation.
  • H319
  • :Causes serious eye irritation.
Precautionary Statements
  • P264
  • :Wash hands and face thoroughly after handling.
  • P270
  • :Do not eat, drink or smoke when using this product.
  • P280
  • :Wear protective gloves, eye protection.
  • P301+P310+P330
  • :IF SWALLOWED: Immediately call a POISON CENTER or doctor. Rinse mouth.
  • P302+P352+P332+P313+P362+P364
  • :IF ON SKIN: Wash with plenty of water. If skin irritation occurs: Get medical advice or attention. Take off contaminated clothing and wash it before reuse.
  • P305+P351+P338+P337+P313
  • :IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists: Get medical advice or attention.

Transport Information

UN Number 2810
Class 6.1
Packing Group III
HS Number 2921490090

Application

Pargyline: An Irreversible Selective MAO-B Inhibitor.

Monoamine oxidase B (MAO-B) is a mitochondrial outer membrane flavoenzyme, which keeps the norepinephrine concentration in the axoplasm low. Therefore, MAO-B is a well-known target for antidepressant and neuroprotective agents. Pargyline is an irreversible selective MAO-B inhibitor. Pargyline is used to treat moderate to severe hypertension. Currently, pargyline is used as an antiparkinson agent. (The product is for research purpose only.)

References

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