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2-Propylvaleric Acid
(CAS RN:99-66-1 Product Number:P0823)

Structure

2-Propylvaleric Acid
Synonym Dipropylacetic Acid
Synonym 2-Propylpentanoic Acid
Synonym Valproic Acid

General Information

Product Number P0823

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Purity/Analysis Method >99.0%(GC)(T)
Storage Temperature
M.F. / M.W. C8H16O2=144.21
CAS RN 99-66-1
Related CAS RN
MDL Number MFCD00002672
Packaging and Container
  • Product Details
  • Safety & Regulations

Specification

Purity(GC) min. 99.0 %
Purity(Neutralization titration) min. 99.0 %
Specific gravity (20/20) 0.9050 to 0.9090
Refractive index n20/D 1.4230 to 1.4260

Data of Reference

flp 126°C(lit.)
bp 220°C

References

Beilstein 2(4)872
Reaxys-RN 1750447
PubChem SID 87574953
Merck Index(14) 9913
RTECS# YV7875000
EC Number 202-777-3

GHS

Pictogram
Signal Word Warning
Hazard Statements
  • H302
  • :Harmful if swallowed.
  • H315
  • :Causes skin irritation.
  • H319
  • :Causes serious eye irritation.
Precautionary Statements
  • P264
  • :Wash hands and face thoroughly after handling.
  • P270
  • :Do not eat, drink or smoke when using this product.
  • P280
  • :Wear protective gloves, eye protection.
  • P301+P312+P330
  • :IF SWALLOWED: Call a POISON CENTER or doctor if you feel unwell. Rinse mouth.
  • P302+P352+P332+P313+P362+P364
  • :IF ON SKIN: Wash with plenty of water. If skin irritation occurs: Get medical advice or attention. Take off contaminated clothing and wash it before reuse.
  • P305+P351+P338+P337+P313
  • :IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists: Get medical advice or attention.

Transport Information

HS Number 2915907090

Application

Valproic Acid: A GABA Enhancer and a HDAC Inhibitor

Valproic acid and its sodium salt [S0894] are one of the major antiepileptic agents. The mechanisms of action have not been established. However, it has been suggested that its activity in epilepsy is related to increased brain concentrations of γ-aminobutyric acid (GABA) [A0282] and dopamine [A0305] in brain.1,2) Furthermore, valproic acid and its sodium salt have recently been shown to inhibit histone deacetylases (HDACs) which play important roles in regulation of gene transcription and pathogenesis of cancer.3-5) (The product is for research purpose only.)

References

PubMed Literature

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