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Pramipexole Dihydrochloride Monohydrate
(CAS RN:191217-81-9 Product Number:P2073)

Structure

Pramipexole Dihydrochloride
Synonym (S)-2-Amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole Dihydrochloride Monohydrate

General Information

Product Number P2073

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Purity/Analysis Method >98.0%(HPLC)(N)
Storage Temperature
M.F. / M.W. C10H17N3S·2HCl·H2O=284.24(as Anhydrous)
CAS RN 191217-81-9
Related CAS RN 104632-25-9,104632-26-0
MDL Number MFCD02183927
Packaging and Container
  • Product Details
  • Safety & Regulations

Specification

Purity(HPLC) min. 98.0 area%
Purity(with Total Nitrogen) min. 98.0 %(calcd.on anh.substance)
Specific rotation [a]20/D -65.0 to -69.0 deg(C=1,MeOH)(calcd.on anh.substance)
Water 5.0 to 7.0 %

References

Reaxys-RN 14116907
PubChem SID 253659970
Merck Index(14) 7705
RTECS# DL3375000

GHS

Pictogram
Signal Word Warning
Hazard Statements
  • H302
  • :Harmful if swallowed.
  • H336
  • :May cause drowsiness or dizziness.
Precautionary Statements
  • P261
  • :Avoid breathing dust/fume/gas/mist/vapours/spray.
  • P264
  • :Wash hands and face thoroughly after handling.
  • P270
  • :Do not eat, drink or smoke when using this product.
  • P304+P340+P312
  • :IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER or doctor if you feel unwell.
  • P403+P233
  • :Store in a well-ventilated place. Keep container tightly closed.
  • P405
  • :Store locked up.

Transport Information

HS Number 2934208090

Application

A Dopamine D3 and D2 Receptor Agonist, Pramipexole

Pramipexole dihydrochloride, which is a dopamine agonist, has selective affinity for dopamine receptors of the D2 subfamily (D2, D3, D4), with a 7-10 fold greater affinity for D3 than for D2 receptor subtypes; affinity for the D4 receptor subtype is 17-fold less than for D3 receptors. For your reference, [D4337] is a key synthetic building block of pramipexole dihydrochloride.

References

PubMed Literature

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