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Quetiapine Hemifumarate
(CAS RN:111974-72-2 Product Number:Q0092)

Structure

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Quetiapine Hemifumarate

General Information

Product Number Q0092

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Purity/Analysis Method >98.0%(HPLC)(T)
Storage Temperature
M.F. / M.W. C21H25N3O21/2C4H4O4=441.55
CAS RN 111974-72-2
Related CAS RN 111974-69-7
MDL Number MFCD03423782
Packaging and Container
  • Product Details
  • Safety & Regulations

Specification

Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 98.0 %
Purity(Neutralization titration) min. 98.0 %
Melting point 172.0 to 176.0 deg-C

References

Reaxys-RN 8378094
PubChem SID 160871365
Merck Index(14) 8039
RTECS# KK3605000

GHS

Pictogram
Signal Word Danger
Hazard Statements
  • H302
  • :Harmful if swallowed.
  • H370
  • :Causes damage to Nervous System.
Precautionary Statements
  • P260
  • :Do not breathe dust, fume, mist, vapours or spray.
  • P264
  • :Wash hands and face thoroughly after handling.
  • P270
  • :Do not eat, drink or smoke when using this product.
  • P301+P312+P330
  • :IF SWALLOWED: Call a POISON CENTER or doctor if you feel unwell. Rinse mouth.
  • P308+P311
  • :If exposed or concerned: Call a POISON CENTER or doctor.
  • P405
  • :Store locked up.

Transport Information

HS Number 2934999090

Application

Quetiapine Hemifumarate: A Multi-Acting Receptor Targeted Antipsychotic (MARTA)

Quetiapine hemifumarate is known as a multi-acting receptor targeted antipsychotic (MARTA), such as clozapine [C2547] and olanzapine [O0393]. Quetiapine has greater affinity for serotonin 5-HT2A and dopamine D1 and D2 receptors. Furthemore, quetiapine has various affinities for multiple receptors, including 5-HT1A and α1- and α2-adrenergic receptors. While, quetiapine binds weakly to benzodiazepine (BZD) and muscarinergic M1A receptors. The precise mechanism of action is unknown, but quetiapine is used as a thienobenzodiazepine atypical antipsychotic. (The product is for research purpose only.)

References

PubMed Literature

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