Home >   Products   >  Advanced Search

Celecoxib
(CAS RN:169590-42-5 Product Number:C2816)

Structure

Celecoxib
Synonym 5-(4-Methylphenyl)-1-(4-sulfamoylphenyl)-3-(trifluoromethyl)pyrazole
Synonym 4-[5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide

General Information

Product Number C2816

* Items available from stock in Japan will be delivered in 10 business days.
* Please contact us if you need further information.
(Sales Dept Tel: +32 (0)3 735 07 00 E-mail: Sales-EU@TCIchemicals.com)
* To send your quote request for bulk quantities, please click on the “Request Bulk Quotation” button. Please note that for some of our products we cannot offer bulk quantities.
* TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.

Purity/Analysis Method >98.0%(HPLC)(T)
Storage Temperature
M.F. / M.W. C17H14F3N3O2S=381.37
CAS RN 169590-42-5
Related CAS RN
MDL Number MFCD00941298
Packaging and Container
  • Product Details
  • Safety & Regulations

Specification

Purity(HPLC) min. 98.0 area%
Purity(Neutralization titration) min. 98.0 %
Melting point 161.0 to 165.0 deg-C

References

Reaxys-RN 7662430
PubChem SID 253660758
Merck Index(14) 1956
RTECS# DB2944937

GHS

Pictogram
Signal Word Warning
Hazard Statements
  • H361fd
  • :Suspected of damaging fertility. Suspected of damaging the unborn child.
  • H373
  • :May cause damage to Cardiovascular System, Intestinal Tract, Stomach through prolonged or repeated exposure.
Precautionary Statements
  • P201
  • :Obtain special instructions before use.
  • P202
  • :Do not handle until all safety precautions have been read and understood.
  • P260
  • :Do not breathe dust, fume, mist, vapours or spray.
  • P280
  • :Wear protective gloves, protective clothing, face protection.
  • P308+P313
  • :IF exposed or concerned: Get medical advice or attention.
  • P405
  • :Store locked up.

Transport Information

HS Number 2935909099

Application

Celecoxib: A Selective Cyclo-Oxygenase-2 (COX-2) Inhibitor

Celecoxib (SC-58635), a nonsteroidal anti-inflammatory drug (NSAID), is a cyclo-oxygenase (COX) inhibitor that exhibits relative selectivity for COX-2 over COX-1 in vitro and in vivo. In theory, a drug such as celecoxib that selectively inhibited COX-2 might block inflammation, pain, and fever produced by prostaglandins while reducing the side effects (gastric erosions and ulcers) associated with inhibition of COX-1. In addition, celecoxib is reported that has anticancer properties.

References

PubMed Literature

Page Top