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Loxoprofen
(CAS RN:68767-14-6 Product Number:L0244)

Structure

Loxoprofen
Synonym 2-[4-[(2-Oxocyclopentyl)methyl]phenyl]propionic Acid

General Information

Product Number L0244

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Purity/Analysis Method >97.0%(HPLC)(T)
Storage Temperature
M.F. / M.W. C15H18O3=246.31
CAS RN 68767-14-6
Related CAS RN
MDL Number MFCD00864331
Packaging and Container
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Specification

Purity(HPLC) min. 97.0 area%
Purity(Neutralization titration) min. 97.0 %

Data of Reference

mp 111°C(lit.)

References

Reaxys-RN 2860055
PubChem SID 354333699
Merck Index(14) 5589

Transport Information

HS Number 2916399090

Application

Loxoprofen: A Prodrug of Non-Steroidal Anti-Inflammatory Drug and a Non-Selective Cyclooxygenase Inhibitor

Loxoprofen is a non-steroidal anti-inflammatory drug (NSAID) in the propionic acid derivatives group, which also includes ibuprofen[I0415], ketoprofen[K0038] and naproxen[M1021] among others. loxoprofen is a prodrug that is rapidly converted to its active trans-alcohol metabolite (loxoprofen-SRS) following oral administration. Loxoprofen is a non-selective cyclooxygenase inhibitor. It works by reducing the synthesis of prostaglandins from arachidonic acid. Loxoprofen has more potent analgesic activity than that of ketoprofen or naproxen. (The product is for research purpose only.)

L0244

References

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