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5-Aza-2'-deoxycytidine
(CAS RN:2353-33-5 Product Number:A2232)

Structure

5-Aza-2'-deoxycytidine
Synonym 5-Aza-1-(2-deoxy-β-D-ribofuranosyl)cytosine
Synonym Decitabine

General Information

Product Number A2232

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Purity/Analysis Method
Storage Temperature 0-10°C
M.F. / M.W. C8H12N4O4=228.21
CAS RN 2353-33-5
Related CAS RN
MDL Number MFCD00043011
Packaging and Container
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Specification

Elemental analysis(Nitrogen) 23.8 to 25.0 %

References

Reaxys-RN 617982
PubChem SID 160871263
Merck Index(14) 2853
RTECS# XZ3012000
EC Number 219-089-4

GHS

Pictogram
Signal Word Warning
Hazard Statements
  • H341
  • :Suspected of causing genetic defects.
Precautionary Statements
  • P201
  • :Obtain special instructions before use.
  • P202
  • :Do not handle until all safety precautions have been read and understood.
  • P280
  • :Wear protective gloves, protective clothing, face protection.
  • P308+P313
  • :IF exposed or concerned: Get medical advice or attention.
  • P405
  • :Store locked up.
  • P501
  • :Dispose of contents/container through a waste management company authorized by the local government.

Transport Information

HS Number 2934999090

Application

An Inhibitor of DNA Methylation

The cytidine analogs 5-aza-2'-deoxycytidine and 5-azacytidine [A2033] are inhibitors of DNA methyltransferases (DNMTs) which catalyze the transfer of a methyl group to DNA. DNA methylation is an epigenetic factor and plays an important role in regulating gene expression. 5-Azacytidine and 5-aza-2'-deoxycytidine are the currently most advanced agents for epigenetic cancer therapies. (The product is for research purpose only.)

References

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