Home >   Products   >  Advanced Search

Abacavir
(CAS RN:136470-78-5 Product Number:A2694)

Structure

zoom
Abacavir
Synonym (1S,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol

General Information

Product Number A2694

* Items available from stock in Japan will be delivered in 10 business days.
* Please contact us if you need further information.
(Sales Dept Tel: +32 (0)3 735 07 00 E-mail: Sales-EU@TCIchemicals.com)
* To send your quote request for bulk quantities, please click on the “Request Bulk Quotation” button. Please note that for some of our products we cannot offer bulk quantities.
* TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.

Purity/Analysis Method >98.0%(HPLC)(T)
Storage Temperature
M.F. / M.W. C14H18N6O=286.34
CAS RN 136470-78-5
Related CAS RN
MDL Number MFCD00903850
Packaging and Container
  • Product Details
  • Safety & Regulations

Specification

Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 98.0 %
Specific rotation [a]20/D -53.0 to -56.0 deg(C=0.15, MeOH)

References

Reaxys-RN 7493116
PubChem SID 253661597
Merck Index(14) 1
RTECS# GY5979200

GHS

Pictogram
Signal Word Danger
Hazard Statements
  • H317
  • :May cause an allergic skin reaction.
  • H334
  • :May cause allergy or asthma symptoms or breathing difficulties if inhaled.
  • H341
  • :Suspected of causing genetic defects.
  • H361fd
  • :Suspected of damaging fertility. Suspected of damaging the unborn child.
Precautionary Statements
  • P261
  • :Avoid breathing dust/fume/gas/mist/vapours/spray.
  • P280
  • :Wear protective gloves, protective clothing, face protection.
  • P284
  • :Wear respiratory protection.
  • P302+P352+P333+P313+P362+P364
  • :IF ON SKIN: Wash with plenty of soap and water. If skin irritation or rash occurs: Take off contaminated clothing. And wash it before reuse.
  • P304+P340+P342+P311
  • :IF INHALED: Remove person to fresh air and keep comfortable for breathing. If experiencing respiratory symptoms: Call a POISON CENTER or doctor.
  • P308+P313
  • :IF exposed or concerned: Get medical advice or attention.

Transport Information

HS Number 2933599590

Application

Abacavir: A Nucleoside Analog Reverse Transcriptase Inhibitor (RTI)

Abacavir is a nucleoside analog reverse transcriptase inhibitor (RTI) that inhibits HIV-1 in vitro with a potency similar to that of zidovudine [A2052]. Resistance to abacavir develops relatively slowly. Cross-resistance between abacavir and other RTIs, namely didanosine [D3066], zalcitabine [D3581] or lamivudine [L0217], but not zidovudine or stavudine [D3580], has been reported in vitro. HLA-B*5701 genetic screening have been reported to prevent drug hypersensitivity reactions caused by abacavir.

References

PubMed Literature

Page Top