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Paclitaxel
(CAS RN:33069-62-4 Product Number:P1632)

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Paclitaxel

General Information

Product Number P1632

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Purity/Analysis Method >98.0%(HPLC)
Storage Temperature
M.F. / M.W. C47H51NO14=853.92
CAS RN 33069-62-4
Related CAS RN
MDL Number
Packaging and Container
  • Product Details
  • Safety & Regulations

Specification

Purity(HPLC) min. 98.0 area%
Purity(with Total Nitrogen) min. 98.0 %
Specific rotation [a]20/D -49.0 to -54.0 deg(C=1, MeOH)

Data of Reference

λmax 227(MeOH)(lit.)

References

Beilstein 18(5)5,622
Reaxys-RN 1420457
PubChem SID 87558555
Merck Index(14) 6982
RTECS# DA8340700

GHS

Pictogram
Signal Word Danger
Hazard Statements
  • H302+H312+H332
  • :Harmful by inhalation, in contact with skin and if swallowed.
  • H315
  • :Causes skin irritation.
  • H317
  • :May cause an allergic skin reaction.
  • H319
  • :Causes serious eye irritation.
  • H334
  • :May cause allergy or asthma symptoms or breathing difficulties if inhaled.
  • H341
  • :Suspected of causing genetic defects.
  • H361fd
  • :Suspected of damaging fertility. Suspected of damaging the unborn child.
Precautionary Statements
  • P261
  • :Avoid breathing dust/fume/gas/mist/vapours/spray.
  • P280
  • :Wear protective gloves, protective clothing, face protection.
  • P284
  • :Wear respiratory protection.
  • P302+P352+P312+P362+P364
  • :IF ON SKIN: Wash with plenty of soap and water. Call a POISON CENTER or doctor if you feel unwell. Take off contaminated clothing and wash it before reuse.
  • P304+P340+P312
  • :IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER or doctor if you feel unwell.
  • P305+P351+P338+P337+P313
  • :IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists: Get medical advice or attention.

Transport Information

HS Number 2932990090

Application

Reagent for pain model

References

  • A painful peripheral neuropathy in the rat produced by the chemotherapeutic drug, paclitaxel
    • R. C. Polomano, A. J. Mannes, U. S. Clark, G. J. Bennett, Pain 2001, 94, 293.
  • Ethosuximide reverses paclitaxel- and vincristine-induced painful peripheral neuropathy

Reviews of the Mechanism of Action of Antitumor Agent Paclitaxel that Interact with Tubulin

References

Reviews on Formulations and Drug Delivery Systems (DDS) of Paclitaxel

References

PubMed Literature

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