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Phloretin
(CAS RN:60-82-2 Product Number:P1966)

Structure

Phloretin
Synonym 3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-1-propanone
Synonym 2',4',6'-Trihydroxy-3-(4-hydroxyphenyl)propiophenone

General Information

Product Number P1966

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Purity/Analysis Method >98.0%(HPLC)
Storage Temperature 0-10°C
M.F. / M.W. C15H14O5=274.27
CAS RN 60-82-2
Related CAS RN
MDL Number MFCD00002288
Packaging and Container
  • Product Details
  • Safety & Regulations

Specification

Purity(HPLC) min. 98.0 area%
Purity(Neutralization titration) min. 95.0 %

Data of Reference

mp 262°C(dec.)(lit.)

References

Reaxys-RN 1887240
PubChem SID 135727056
Merck Index(14) 7326
EC Number 200-488-7

GHS

Pictogram
Signal Word Warning
Hazard Statements
  • H315
  • :Causes skin irritation.
  • H319
  • :Causes serious eye irritation.
Precautionary Statements
  • P264
  • :Wash hands and face thoroughly after handling.
  • P280
  • :Wear protective gloves, eye protection.
  • P302+P352+P332+P313+P362+P364
  • :IF ON SKIN: Wash with plenty of water. If skin irritation occurs: Get medical advice or attention. Take off contaminated clothing and wash it before reuse.
  • P305+P351+P338+P337+P313
  • :IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists: Get medical advice or attention.

Transport Information

HS Number 2914500090

Application

Phloretin: A Dihydrochalcone with Many Interesting Biological Properties

Phloretin is a dihydrochalcone and a polyphenol, can be found in apple tree leaves. Phloretin and its glycosylated derivative (phlorizin [P0248]) have many interesting biological properties. For example, phloretin inhibits sodium glucose co-transporters (SGLTs), though the inhibition is weaker than by phlorizin. In addition, phloretin shows an antioxidant activity in peroxynitrite scavenging and the inhibition of lipid peroxidation.

References

PubMed Literature

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