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Paromomycin Sulfate
(CAS RN:1263-89-4 Product Number:P2092)

Structure

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Paromomycin Sulfate

General Information

Product Number P2092

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Purity/Analysis Method >94.0%(HPLC)
Storage Temperature
M.F. / M.W. C23H45N5O14·xH2SO4
CAS RN 1263-89-4
Related CAS RN 7542-37-2,84420-34-8
MDL Number MFCD00079278
Packaging and Container
  • Product Details
  • Safety & Regulations

Specification

Purity(HPLC) min. 94.0 area%
Specific rotation [a]20/D +47.0 to +55.0 deg(C=1, H2O)

References

PubChem SID 253662559
Merck Index(14) 7041
RTECS# WK2320000
EC Number 215-031-7

GHS

Pictogram
Signal Word Warning
Hazard Statements
  • H315
  • :Causes skin irritation.
  • H319
  • :Causes serious eye irritation.
Precautionary Statements
  • P264
  • :Wash hands and face thoroughly after handling.
  • P280
  • :Wear protective gloves, eye protection.
  • P302+P352+P332+P313+P362+P364
  • :IF ON SKIN: Wash with plenty of water. If skin irritation occurs: Get medical advice or attention. Take off contaminated clothing and wash it before reuse.
  • P305+P351+P338+P337+P313
  • :IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists: Get medical advice or attention.

Transport Information

HS Number 2941900000

Application

Paromomycin: An Aminoglycoside Antibiotic against Bacteria, Protozoa and Cestodes

Paromomycin is an aminoglycoside antibiotic, first isolated from various Streptomyces in the 1950s. It is active against Gram-negative and many Gram-positive bacteria as well as some protozoa and cestodes. Paromomycin irreversibly binds to the 30S subunit (16S rRNA) of the bacterial ribosome as with any other aminoglycoside antibiotics, and then it inhibits bacterial growth by inhibiting protein synthesis. Paromomycin is mainly used for treatment of leishmaniasis and amoebic dysentery. (The product is for research purpose only.)

References

PubMed Literature

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