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Scopolamine Hydrobromide Trihydrate
(CAS RN:6533-68-2 Product Number:S0021)

Structure

Scopolamine Hydrobromide

General Information

Product Number S0021

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Purity/Analysis Method >98.0%(HPLC)(T)
Storage Temperature
M.F. / M.W. C17H21NO4·HBr·3H2O=384.27(as Anhydrous)
CAS RN 6533-68-2
Related CAS RN 114-49-8,51-34-3
MDL Number MFCD00012647
Packaging and Container
  • Product Details
  • Safety & Regulations

Specification

Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 98.0 %(after drying)
Specific rotation [a]20/D -24.0 to -27.0 deg(C=5, H2O)(after drying)
Solubility in Water almost transparency
Drying loss max. 13.0 %

References

Beilstein 27,102
Reaxys-RN 6100669
PubChem SID 87575651
Merck Index(14) 8406
RTECS# YM4550000
EC Number 204-050-6

GHS

Pictogram
Signal Word Warning
Hazard Statements
  • H302
  • :Harmful if swallowed.
Precautionary Statements
  • P264
  • :Wash hands and face thoroughly after handling.
  • P270
  • :Do not eat, drink or smoke when using this product.
  • P301+P312+P330
  • :IF SWALLOWED: Call a POISON CENTER or doctor if you feel unwell. Rinse mouth.
  • P501
  • :Dispose of contents/container through a waste management company authorized by the local government.

Transport Information

UN Number 1544
Class 6.1
Packing Group III
HS Number 2939790090

Application

Scopolamine Hydrobromide: A Belladonna Alkaloid with Anticholinergic Activity

Scopolamine salts ([S0021][ S0230] and [S0231]) and N-oxide [S0229], belladonna alkaloids, are anticholinergic agents. Their free base, scopolamine competitively inhibits muscarinic receptors of the parasympathetic nervous system for acetylcholine and act as a nonselective muscarinic antagonist, producing peripheral anti-muscarinic, central sedative and antiemetic effects. The parasympatholytic scopolamine, structurally very similar to atropine [A0754] as well, is used in conditions requiring decreased parasympathetic activity. Therefore, scopolamine can inhibit the secretion of saliva and sweat, decrease gastrointestinal secretions and motility, and increase heart rate et al. (The product is for research purpose only.)

References

Reagent for experimental amnesia (Alzheimer's disease) model

References

PubMed Literature

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