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Terazosin Hydrochloride Dihydrate
(CAS RN:70024-40-7 Product Number:T2751)

Structure

Terazosin Hydrochloride
Synonym 4-Amino-6,7-dimethoxy-2-[4-(tetrahydro-2-furoyl)-1-piperazinyl]quinazoline Hydrochloride Dihydrate

General Information

Product Number T2751

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Purity/Analysis Method >98.0%(HPLC)(N)
Storage Temperature
M.F. / M.W. C19H25N5O4·HCl·2H2O=423.90(as Anhydrous)
CAS RN 70024-40-7
Related CAS RN 63074-08-8,63590-64-7
MDL Number MFCD00941408
Packaging and Container
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Specification

Purity(HPLC) min. 98.0 area%
Purity(with Total Nitrogen) min. 98.0 %(calcd.on anh.substance)
Water 7.0 to 9.0 %

Data of Reference

mp 274°C(lit.)

References

Reaxys-RN 6495493
PubChem SID 125307764
RTECS# TK8046000

Transport Information

HS Number 2934999090

Application

Terazosin Hydrochloride: A Long Acting α1-Selective Adrenoceptor Antagonist

Terazosin hydrochloride, a quinazoline derivative, is a long acting α1-selective adrenoceptor antagonist with a similar pharmacodynamic profile to prazosin [P0938]. Terazosin is known to relax vascular and prostate smooth muscle through blockade of α1-adrenoceptors, and lowers blood pressure by decreasing peripheral vascular resistance. In in vitro experiments, terazosin has been shown to contractions in human prostatic tissue, and it is used in the treatment for prostatic hyperplasia (BPH). In addition, some studies indicate that α1-selective adrenoceptor antagonists show suppression of human prostate cancer cell growth. (The product is for research purpose only.)

References

PubMed Literature

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