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Tetrandrine
(CAS RN:518-34-3 Product Number:T3321)

Structure

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Tetrandrine
Synonym (1β)-6,6',7,12-Tetramethoxy-2,2'-dimethylberbaman

General Information

Product Number T3321

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Purity/Analysis Method >98.0%(HPLC)(T)
Storage Temperature
M.F. / M.W. C38H42N2O6=622.76
CAS RN 518-34-3
Related CAS RN
MDL Number MFCD08689909
Packaging and Container
  • Product Details
  • Safety & Regulations

Specification

Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 98.0 %
Melting point 221.0 to 225.0 deg-C
Specific rotation [a]20/D +283 to +287 deg(C=1,CHCl3)

Data of Reference

λmax 283(EtOH)(lit.)

References

Reaxys-RN 79006
PubChem SID 253661357
Merck Index(14) 9231
RTECS# XE9350000

GHS

Pictogram
Signal Word Warning
Hazard Statements
  • H302
  • :Harmful if swallowed.
Precautionary Statements
  • P264
  • :Wash hands and face thoroughly after handling.
  • P270
  • :Do not eat, drink or smoke when using this product.
  • P301+P312+P330
  • :IF SWALLOWED: Call a POISON CENTER or doctor if you feel unwell. Rinse mouth.
  • P501
  • :Dispose of contents/container through a waste management company authorized by the local government.

Transport Information

HS Number 2934999090

Application

Tetrandrine: A Bisbenzylisoquinoline Alkaloid with Broad Pharmacological Activities

Tetrandrine is a bisbenzylisoquinoline alkaloid isolated from the dried root of Stephenia tetrandra S Moore which is a plant indigenous to main land of China that has long been used as a Chinese herb. Recently, several studies have demonstrated that tetrandrine is a calcium channel receptor antagonist. Moreover, tetrandrine exhibits broad pharmacological activities, including antihypertensive, antiarrhythmic and antitumor activities. Tetrandrine has also been shown to inhibit infection of human macrophages, the primary target of Ebola virus, and also showed therapeutic efficacy in mice. (The product is for research purpose only.)

References

PubMed Literature

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