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4-(p-Tolylthio)thieno[2,3-c]pyridine-2-carboxamide
(CAS RN:251992-66-2 Product Number:T3498)

Structure

4-(p-Tolylthio)thieno[2,3-c]pyridine-2-carboxamide
Synonym A 205804
Synonym 4-[(4-Methylphenyl)thio]thieno[2,3-c]pyridine-2-carboxamide

General Information

Product Number T3498

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Purity/Analysis Method >95.0%(HPLC)
Storage Temperature 0-10°C
M.F. / M.W. C15H12N2OS2=300.39
CAS RN 251992-66-2
Related CAS RN
MDL Number MFCD09038566
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Specification

Purity(HPLC) min. 95.0 area%
Elemental analysis(Nitrogen) 8.80 to 9.80 %
Melting point 198.0 to 202.0 deg-C

References

Reaxys-RN 8847872
PubChem SID 354334760

Transport Information

HS Number 2934999090

Application

An Inhibitor of the Induced Expression of Intercellular Adhesion Molecule-1 (ICAM-1) and E-Selection

It is reported that this compound is a potent and selective inhibitor of the induced expression of E-selection and intercellular adhesion molecule-1 (ICAM-1) relative to vascular cell adhesion molecule-1 (VCAM-1). For your information, E-selectin, ICAM-1, and VCAM-1 play a role in cell adhesion to the vascular endothelium. E-selectin is expressed on inflamed vascular endothelial cells in response to treatment with inflammatory cytokines.

References

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