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Valacyclovir Hydrochloride
(CAS RN:124832-27-5 Product Number:V0111)

Structure

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Valacyclovir Hydrochloride
Synonym L-Valine 2-(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-ylmethoxy)ethyl Ester Hydrochloride

General Information

Product Number V0111

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Purity/Analysis Method >97.0%(HPLC)(N)
Storage Temperature
M.F. / M.W. C13H20N6O4·HCl=360.80
CAS RN 124832-27-5
Related CAS RN 1218948-84-5,124832-26-4
MDL Number MFCD01861507
Packaging and Container
  • Product Details
  • Safety & Regulations

Specification

Purity(HPLC) min. 97.0 area%
Purity(with Total Nitrogen) min. 97.0 %(calcd.on anh.substance)
Water max. 6.0 %

Data of Reference

λmax 253(H2O)(lit.)

References

Reaxys-RN 14243859
PubChem SID 125307930
Merck Index(14) 9899

GHS

Pictogram
Signal Word Warning
Hazard Statements
  • H302
  • :Harmful if swallowed.
Precautionary Statements
  • P264
  • :Wash hands and face thoroughly after handling.
  • P270
  • :Do not eat, drink or smoke when using this product.
  • P301+P312+P330
  • :IF SWALLOWED: Call a POISON CENTER or doctor if you feel unwell. Rinse mouth.
  • P501
  • :Dispose of contents/container through a waste management company authorized by the local government.

Transport Information

HS Number 2933599590

Application

Valacyclovir Hydrochloride: A Prodrug of Antiviral Acyclovir

Valacyclovir hydrochloride is a prodrug of antiviral acyclovir [A1915] which is a nucleoside analog DNA polymerase inhibitor. It was developed to improve the pharmacokinetic characteristics of acyclovir. After oral administration, valacyclovir hydrochloride is rapidly absorbed from the gastrointestinal tract by the intestinal peptide transporter (PEPT1) and converted to acyclovir and L-valine [V0014] by first-pass intestinal and/or hepatic metabolism. (The product is for research purpose only.)

References

PubMed Literature

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