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7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid
(CAS RN:86393-33-1 Product Number:C2293)


7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid
Synonym Fluoroquinolonic Acid

General Information

Product Number C2293

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Purity/Analysis Method >98.0%(HPLC)(T)
Storage Temperature
M.F. / M.W. C13H9ClFO3N=281.67
CAS RN 86393-33-1
Related CAS RN
MDL Number MFCD00792458
Packaging and Container
  • Product Details
  • Safety & Regulations


Purity(HPLC) min. 98.0 area%
Purity(Neutralization titration) min. 98.0 %


Reaxys-RN 4515704
PubChem SID 87560826
RTECS# VB1993795
EC Number 405-050-0


Signal Word Warning
Hazard Statements
  • H302
  • :Harmful if swallowed.
  • H412
  • :Harmful to aquatic life with long lasting effects.
Precautionary Statements
  • P264
  • :Wash hands and face thoroughly after handling.
  • P270
  • :Do not eat, drink or smoke when using this product.
  • P273
  • :Avoid release to the environment.
  • P301+P312+P330
  • :IF SWALLOWED: Call a POISON CENTER or doctor if you feel unwell. Rinse mouth.
  • P501
  • :Dispose of contents/container through a waste management company authorized by the local government.

Transport Information

HS Number 2933491090


Amination with morpholine derivatives under microwave irradiation


Synthesis and metabolic evaluation of azaspirocyclic fluoroquinolones

Typical procedure: KOtBu (191 mg) is dissolve in DMSO (20 mL), azetidinium oxalate (164 mg) is added and the mixture is stirred at rt for 10 min. Then, 7-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid (200 mg) is added, and the yellow mixture is heated to 130 ºC and stirred for 5.5 h. Then it is cooled to rt and poured into H2O (75 mL). The precipitate is filtered and dried overnight upon standing. The crude product is purified by suspending in hot CHCl3, and cooling the mixture to rt, when it is filtered. The residue is dried in vacuo to give the pure desired product (166 mg, 68 %).


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