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Fosfomycin Disodium Salt
(CAS RN:26016-99-9 Product Number:F0889)

Structure

Fosfomycin Disodium Salt
Synonym Disodium (1R,2S)-1,2-Epoxypropylphosphonate
Synonym (1R,2S)-1,2-Epoxypropylphosphonic Acid Disodium Salt
Synonym Phosphomycin Disodium Salt

General Information

Product Number F0889

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Purity/Analysis Method >98.0%(HPLC)(T)
Storage Temperature 0-10°C
M.F. / M.W. C3H5Na2O4P=182.02
CAS RN 26016-99-9
Related CAS RN 23155-02-4
MDL Number MFCD00056853
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Specification

Purity(HPLC)(CAD) min. 98.0 area%
Purity(Nonaqueous Titration) min. 98.0 %
Specific rotation [a]20/D -3.5 to -5.5 deg(C=5, H2O)

References

Reaxys-RN 4604425
PubChem SID 253660394
RTECS# SZ7902000
EC Number 247-409-2

Transport Information

HS Number 2931909099

Application

Fosfomycin: A Broad-Spectrum Antibiotic with Inactivating UDP-N-Acetylglucosamine-3-enolpyruvyl Transferase (MurA)

Fosfomycin (also known as phosphomycin), a broad-spectrum antibiotic, was isolated from Streptomyces fradiase in 1969. It can now be made by chemical synthesis. Fosfomycin has bactericidal activity against a wide range of bacteria, including Gram-negative micro-organisms and some Gram-positive bacteria, such as staphylococci. Fosfomycin interferes with cell wall synthesis in bacteria by inhibiting the initial step by inactivating UDP-N-acetylglucosamine-3-enolpyruvyl transferase, also known as MurA.

References

PubMed Literature

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