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Granisetron Hydrochloride
(CAS RN:107007-99-8 Product Number:G0401)


Granisetron Hydrochloride
Synonym 1-Methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide Hydrochloride

General Information

Product Number G0401

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Purity/Analysis Method >98.0%(HPLC)(T)
Storage Temperature
M.F. / M.W. C18H24N4O·HCl=348.88
CAS RN 107007-99-8
Related CAS RN 109889-09-0
MDL Number MFCD01747034
Packaging and Container
  • Product Details
  • Safety & Regulations


Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 98.0 %

Data of Reference

mp 292°C(dec.)(lit.)


Reaxys-RN 3640184
PubChem SID 172089139
Merck Index(14) 4536
RTECS# NK7882200


Signal Word Warning
Hazard Statements
  • H302
  • :Harmful if swallowed.
Precautionary Statements
  • P264
  • :Wash hands and face thoroughly after handling.
  • P270
  • :Do not eat, drink or smoke when using this product.
  • P301+P312+P330
  • :IF SWALLOWED: Call a POISON CENTER or doctor if you feel unwell. Rinse mouth.
  • P501
  • :Dispose of contents/container through a waste management company authorized by the local government.

Transport Information

HS Number 2939790090


Granisetron Hydrochloride: A Potent and Highly Selective 5-Hydroxytryptamine 3 (5-HT3) Receptor Antagonist

Granisetron hydrochloride is a potent and highly selective 5-hydroxytryptamine 3 (5-HT3) receptor antagonist that has little or no affinity for other serotonin receptors, including 5-HT1; 5-HT1A; 5-HT1B/C; 5-HT2; for α1-, α2- or β-adrenergic receptors; for dopamine-D2; or for histamine-H1; benzodiazepine; picrotoxin or opioid receptors. 5-HT3 receptors are located peripherally on vagal nerve terminals and centrally in the chemoreceptor trigger zone (CTZ) of the area postrema, known as the emetic center of the brain. Therefore, granisetron is used for the prevention of chemotherapy-induced nausea and vomiting. (The product is for research purpose only.)


PubMed Literature

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