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Rabeprazole Sodium Salt
(CAS RN:117976-90-6 Product Number:R0115)

Structure

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Rabeprazole Sodium Salt

General Information

Product Number R0115

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Purity/Analysis Method >98.0%(HPLC)
Storage Temperature <0°C
M.F. / M.W. C18H20N3NaO3S=381.43
CAS RN 117976-90-6
Related CAS RN 117976-89-3
MDL Number MFCD02092688
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Specification

Purity(HPLC) min. 98.0 area%
Purity(with Total Nitrogen) min. 95.0 %

Data of Reference

mp 150°C(lit.)

References

Reaxys-RN 7561607
PubChem SID 253660182
Merck Index(14) 8089

Transport Information

HS Number 2933399990

Application

A More Potent Proton Pump Inhibitor, Rabeprazole Sodium

Rabeprazole sodium is a new substituted benzimidazole proton pump inhibitor with several differences compared with existing proton pump inhibitors. Rabeprazole sodium is a more potent inhibitor of H+,K+-ATPase (hydrogen-potassium adenosine triphosphatase) and acid secretion than omeprazole [O0359], and is a more rapid inhibitor of proton pumps than omeprazole, lansoprazole [L0233], or pantoprazole sulfide [P2066]. Furthermore, in vitro studies have shown that rabeprazole sodium possesses more potent antibacterial properties against the growth of H. pylori than other proton pump inhibitors.

References

PubMed Literature

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