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Homobifunctional Cross-Linkers

 Bi-reactive compounds with the same active groups on both terminals of a linker are called "homo"-bifunctinal crosslinkers. PEG (Polyethylene Glycol) or acyl (fatty) chains are primarily used as linkers to connect these two identical reactive ends. Typical active groups include, Carboxyl group or NHS (N-hydroxysuccinimide) ester for crosslinking amines on the target molecule, Amino group or Hydrazide group for crosslinking carboxylic acids, Thiol group (disulfide bond forming) and maleimide group for reacting with thiols on the target molecule, etc. For bonding amine to carboxylic acid, peptide bond is formed by using EDC, CMC, DCC, DIC, and others as condensing agents. Homobifunctional Crosslinkers are used for connecting various biomolecules and low molecular compounds.
A0170
Adipic Dihydrazide
A0806
Dimethyl Adipimidate Dihydrochloride [Cross-linking Agent for Protein Research]
B0964
1,4-Butanediol Diglycidyl Ether
B1431
1,2-Bis(2-aminoethoxy)ethane
B1787
1,6-Bis(maleimido)hexane
B3728
Bis(NHS)PEG5
B3790
Bis[2-(4-azidosalicylamido)ethyl] Disulfide
B3805
1,4-Bis(maleimido)butane
B4688
Bis(NHS)PEG9
B4911
tert-Butyl Hydrogen Hexadecanedioate
B5141
N-(tert-Butoxycarbonyl)-2,2'-(ethylenedioxy)diethylamine
B5667
1,8-Bis(maleimido)-3,6-dioxaoctane
B5668
1,11-Bis(maleimido)-3,6,9-trioxaundecane
B5683
N-(tert-Butoxycarbonyl)-2-(2-aminoethoxy)ethylamine
B5699
Bis(2-maleimidoethyl) Disulfide
B5779
Bis(3-sulfo-N-succinimidyl) Suberate Disodium Salt
B5926
tert-Butyl Hydrogen Dodecanedioate
B5927
tert-Butyl Hydrogen Tetradecanedioate
B5928
18-(tert-Butoxy)-18-oxooctadecanoic Acid
D0536
Bis(4-fluoro-3-nitrophenyl) Sulfone
D0945
Dithiodiglycolic Acid
D0947
3,3'-Dithiodipropionic Acid
D1571
Diethylene Glycol Bis(3-aminopropyl) Ether
D1649
1,5-Difluoro-2,4-dinitrobenzene
D1662
Di(N-succinimidyl) Carbonate
D1757
4,4'-Dithiodibutyric Acid
D2473
Di(N-succinimidyl) 3,3'-Dithiodipropionate [Cross-linking Reagent]
D3664
1,11-Diamino-3,6,9-trioxaundecane
D3895
Di(N-succinimidyl) Suberate
D4019
Di(N-succinimidyl) Sebacate
D4581
Diethylene Glycol Bis(2-propynyl) Ether
D5500
Di(N-succinimidyl) L-Tartrate
D5622
Disuccinimidyl Succinate
E0482
1,2-Bis(maleimido)ethane
E1054
Ethylene Glycol 1,2-Bis(2-propynyl) Ether
E1269
Ethylene Glycol Bis(3-mercaptopropionate)
E1329
Ethylene Glycol Bis(3-mercaptopropionate) (Purified)
E1333
Ethylene Bis(thioglycolate) (Purified)
G0067
Glutaraldehyde (24-26% in Water)
G0068
Glutaraldehyde (ca. 50% in Water, ca. 5.6mol/L)
M3033
Mono-tert-butyl Succinate
M3206
Malonic Acid Dihydrazide
N1160
N,N'-(Naphthalene-1,5-diyl)bis[2-(aminooxy)acetamide]
P0892
Dimethyl Pimelimidate Dihydrochloride [Cross-linking Agent for Peptides Research]
P1948
Polyethylene Glycol Bis(3-aminopropyl) Ether
P2335
Propargyl Ether
S0246
Dimethyl Suberimidate Dihydrochloride [Cross-linking Agent for Protein Research]
T3198
1,14-Diamino-3,6,9,12-tetraoxatetradecane
T3241
5,6,11,12-Tetradehydrodibenzo[a,e]cyclooctene

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