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Anti-6-sulfo LacNAc Monoclonal Antibody (AG105)
(Product Number:A3251)

Structure

Anti-6-sulfo LacNAc Monoclonal Antibody (AG105)

General Information

Product Number A3251

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Purity/Analysis Method
Storage Temperature -80°C
M.F. / M.W.
CAS RN
Related CAS RN
MDL Number
Packaging and Container
  • Product Details
  • Safety & Regulations

Specification

Titer to pass test

Transport Information

HS Number 3002190000

Application

Anti-6-sulfo LacNAc Monoclonal Antibody (AG105)

References

  • Expression of sialyl 6-sulfo Lewis X is inversely correlated with conventional sialyl Lewis X expression in human colorectal cancer.
    • M. Izawa, K. Kumamoto, C. Mitsuoka, A. Kanamori, K. Ohmori, H. Ishida, S. Nakamura, K. Kurata-Miura, K. Sasaki, T Nishi, R Kannagi, Cancer Res. 2000, 60, 1410.
  • 6-Sulfo LacNAc, a novel carbohydrate modification of PSGL-1, defines an inflammatory type of human dendritic cells.
    • K. Schäkel, R. Kannagi, B. Kniep, Y. Goto, C. Mitsuoka, J. Zwirner, A. Soruri, M. von Kietzell, E. P. Rieber, Immunity 2002, 17, 289.
  • TNF-α increases the carbohydrate sulfation of CD44: induction of 6-sulfo N-acetyl lactosamine on N- and O-linked glycans.
  • Expression of N-acetylglucosamine 6-O-sulfotransferases (GlcNAc6STs)-1 and -4 in human monocytes: GlcNAc6ST-1 is implicated in the generation of the 6-sulfo N-acetyllactosamine/Lewis x epitope on CD44 and is induced by TNF-α.
  • Anti-oligosaccharide antibodies as tools for studying sulfated sialoglycoconjugate ligands for siglecs and selectins

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