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Published TCIMAIL newest issue No.198
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CAS RN: 23496-41-5 | Product Number: P2610
Peimine
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Purity: >98.0%(HPLC)
Synonyms:
- Verticine
- (3β,5α,6α)-Cevane-3,6,20-triol
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 5MG |
€63.00
|
Contact Us | 22 |
|
| 25MG |
€237.00
|
Contact Us | 32 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | P2610 |
Purity / Analysis Method 
|
>98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__7H__4__5NO__3 = 431.66 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Heat Sensitive |
| CAS RN | 23496-41-5 |
| Reaxys Registry Number | 93323 |
| PubChem Substance ID | 468592634 |
| Merck Index (14) | 9969 |
| MDL Number | MFCD02259442 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC)(CAD) | min. 98.0 area% |
| Specific rotation [a]20/D | -18.0 to -23.0 deg(C=0.2, ethanol) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 223 °C |
| Specific Rotation | -20° (C=0.2,EtOH) |
GHS
Related Laws:
Transport Information:
| HS Number | 2939799090 |
Application
Peimine: A Bioactive Alkaloid with Antitussive, Expectorant and Anti-Inflammatory Activities
Peimine (verticine) and peiminine (verticinone) [P2609] are major active alkaloids isolated from the bulbs of Fritillaria ussuriensis, which is an Asian species of herbaceous plant in the lily family and a commonly used antitussive traditional Chinese medicinal (TCM) herb.1,2) It has been reported that peimine and peiminine also exhibit potent antitussive, expectorant and anti-inflammatory effects.3,4) In addition, peimine inhibits telomerase activity and thus may act as an antitumor agent.5) (The product is for research purpose only.)
References
- 1) Determination of the major isosteroidal alkaloids in bulbs of Fritillaria by high-performance liquid chromatography coupled with evaporative light scattering detection
- 2) Characterization and identification of steroidal alkaloids in Fritillaria species using liquid chromatography coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry
- 3) Antitussive, expectorant and anti-inflammatory alkaloids from Bulbus Fritillariae Cirrhosae
- 4) Peimine, a main active ingredient of Fritillaria, exhibits anti-inflammatory and pain suppression properties at the cellular level
- 5) Stabilizing parallel G-quadruplex DNA by a new class of ligands: two non-planar alkaloids through interaction in lateral grooves
Product Documents (Note: Some products will not have analytical charts available.)
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