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Etofibrate
(CAS RN:31637-97-5 Product Number:E1359)

Structure

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Etofibrate
Synonym 2-[2-(4-Chlorophenoxy)-2-methyl-1-oxopropoxy]ethyl 3-Pyridinecarboxylate
Synonym 2-[[2-(4-Chlorophenoxy)-2-methylpropanoyl]oxy]ethyl Nicotinate
Synonym Nicotinic Acid 2-[[2-(4-Chlorophenoxy)-2-methylpropanoyl]oxy]ethyl Ester
Synonym 3-Pyridinecarboxylic Acid 2-[2-(4-Chlorophenoxy)-2-methyl-1-oxopropoxy]ethyl Ester

General Information

Product Number E1359

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Purity/Analysis Method >98.0%(GC)
Storage Temperature 0-10°C
M.F. / M.W. C18H18ClNO5=363.79
CAS RN 31637-97-5
Related CAS RN
MDL Number MFCD00865727
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Specification

Purity(GC) min. 98.0 %
Melting point 48.0 to 52.0 deg-C

Data of Reference

bp 214°C/0.3mmHg(lit.)

References

Reaxys-RN 497931
Merck Index(14) 3877
EC Number 250-743-1

Transport Information

HS Number 2933399990

Application

Etofibrate: A Hybrid Hypolipidemic Agent which Combines Nicotinic Acid (Niacin) with Clofibrate

Etofibrate is a hypolipidemic fibrate which combines nicotinic acid (niacin) [N0082] with clofibrate [C0941]. After contact with plasma hydrolases, both active constituents are gradually released in a controlled-release manner. The fibrates, including etofibrate, are lower elevated serum lipids by decreasing the low density lipoprotein (LDL) fraction rich in cholesterol and the very low density lipoprotein (VLDL) fraction rich in triglycerides. In addition, fibrates increase the high density lipoprotein (HDL) cholesterol fraction. (The product is for research purpose only.)

References

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