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N-Formyl-L-methionyl-L-leucyl-L-phenylalanine
(CAS RN:59880-97-6 Product Number:F1158)

Structure

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N-Formyl-L-methionyl-L-leucyl-L-phenylalanine
Synonym fMLF
Synonym fMLP
Synonym N-Formyl-Met-Leu-Phe

General Information

Product Number F1158

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Purity/Analysis Method >98.0%(HPLC)
Storage Temperature <0°C
M.F. / M.W. C21H31N3O5S=437.56
CAS RN 59880-97-6
Related CAS RN
MDL Number MFCD00036780
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Specification

Purity(HPLC) min. 98.0 area%
Specific rotation [a]20/D -8.0 ~ -10.0 deg(C=1, acetic acid)

References

Reaxys-RN 2315783

Transport Information

HS Number 2930909899

Application

fMLP: A Highly Potent Leukocyte Chemoattractant

N-Formyl-Met-Leu-Phe (abbrev.: fMLP or FMLP), a bacterial peptide, is a highly potent leukocyte chemoattractant. It is a powerful "activators" of polymorphonuclear and mononuclear phagocytes. Its specific receptors have been identified on neutrophil plasma membrane which plays an important role in host defense against bacterial infections.

References

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