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Rifabutin
(CAS RN:72559-06-9 Product Number:R0211)

Structure

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Rifabutin
Synonym Ansamycin
Synonym LM-427

General Information

Product Number R0211

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Purity/Analysis Method >98.0%(HPLC)
Storage Temperature <0°C
M.F. / M.W. C46H62N4O11=847.02
CAS RN 72559-06-9
Related CAS RN
MDL Number MFCD00866816
Packaging and Container
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Specification

Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 97.0 %
Melting point 154.0 to 158.0 deg-C

Data of Reference

λmax 493(MeOH)(lit.)

References

Reaxys-RN 3584778
Merck Index(14) 8213
RTECS# VJ6700000

Transport Information

HS Number 2941900000

Application

Rifabutin: a derivative of rifamycin S with anti-mycobacteria activity

Rifabutin is a derivative of rifamycin S [R0200], belonging to the class of ansamycins, with activity against mycobacteria including atypical organisms such as Mycobacterium avium and M. intracellulare, also referred to as Mycobacterium avium-intracellulare complex (MAC). Rifabutin inhibits DNA-dependent RNA polymerase in susceptible strains of Escherichia coli and Bacillus subtilis but not in mammalian cells. (The product is for research purpose only.)

References

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