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Abiraterone
(CAS RN:154229-19-3 Product Number:A2868)

Structure

Abiraterone
Synonym 17-(3-Pyridyl)androsta-5,16-dien-3β-ol

General Information

Product Number A2868

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Purity/Analysis Method >98.0%(HPLC)
Storage Temperature 0-10°C
M.F. / M.W. C24H31NO=349.52
CAS RN 154229-19-3
Related CAS RN
MDL Number MFCD00924100
Packaging and Container
  • Product Details
  • Safety & Regulations

Specification

Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 97.0 %
Melting point 226.0 to 230.0 deg-C

References

Reaxys-RN 7309269
PubChem SID 253661112

GHS

Pictogram
Signal Word Warning
Hazard Statements
  • H361fd
  • :Suspected of damaging fertility. Suspected of damaging the unborn child.
  • H373
  • :May cause damage to Liver through prolonged or repeated exposure.
Precautionary Statements
  • P201
  • :Obtain special instructions before use.
  • P202
  • :Do not handle until all safety precautions have been read and understood.
  • P260
  • :Do not breathe dust, fume, mist, vapours or spray.
  • P280
  • :Wear protective gloves, protective clothing, face protection.
  • P308+P313
  • :IF exposed or concerned: Get medical advice or attention.
  • P405
  • :Store locked up.

Transport Information

HS Number 2933399990

Application

Abiraterone: A Selective Inhibitor of the Steroidogenic Enzyme Cytochrome P450 17A1 (CYP17A1)

Abiraterone is a selective inhibitor of the steroidogenic enzyme cytochrome P450 17A1 (CYP17A1) which catalyzes two key serial reactions (17α-hydroxylase hydroxylase and 17,20-lyase) in androgen and estrogen biosynthesis. Abiraterone acetate [A2891] (of which the active metabolite is abiraterone) is an agent used in combination with prednisone [P1276] in metastatic castration-resistant prostate cancer (mCRPC). (The product is for research purpose only.)

References

PubMed Literature

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