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Baclofen
(CAS RN:1134-47-0 Product Number:B3343)

Structure

Baclofen
Synonym 4-Amino-3-(4-chlorophenyl)butyric Acid

General Information

Product Number B3343

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Purity/Analysis Method >98.0%(T)
Storage Temperature
M.F. / M.W. C10H12ClNO2=213.66
CAS RN 1134-47-0
Related CAS RN
MDL Number MFCD00055143
Packaging and Container
  • Product Details
  • Safety & Regulations

Specification

Purity(Nonaqueous Titration) min. 98.0 %

Data of Reference

mp 208°C(lit.)

References

Reaxys-RN 2104494
PubChem SID 87561134
Merck Index(14) 937
RTECS# MW5084200
EC Number 214-486-9

GHS

Pictogram
Signal Word Danger
Hazard Statements
  • H301
  • :Toxic if swallowed.
  • H315
  • :Causes skin irritation.
  • H317
  • :May cause an allergic skin reaction.
  • H319
  • :Causes serious eye irritation.
  • H334
  • :May cause allergy or asthma symptoms or breathing difficulties if inhaled.
Precautionary Statements
  • P261
  • :Avoid breathing dust/fume/gas/mist/vapours/spray.
  • P284
  • :Wear respiratory protection.
  • P301+P310+P330
  • :IF SWALLOWED: Immediately call a POISON CENTER or doctor. Rinse mouth.
  • P302+P352+P333+P313+P362+P364
  • :IF ON SKIN: Wash with plenty of soap and water. If skin irritation or rash occurs: Take off contaminated clothing. And wash it before reuse.
  • P304+P340+P342+P311
  • :IF INHALED: Remove person to fresh air and keep comfortable for breathing. If experiencing respiratory symptoms: Call a POISON CENTER or doctor.
  • P305+P351+P338+P337+P313
  • :IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists: Get medical advice or attention.

Transport Information

UN Number 2811
Class 6.1
Packing Group III
HS Number 2922498590

Application

Baclofen: A γ-Amino Butyric Acid Type B (GABAB) Receptor Agonist

Baclofen is a γ-amino butyric acid type B (GABAB) receptor agonist. Baclofen is a muscle relaxant and antispastic, but the precise mechanism of action of baclofen is not fully understood. However, baclofen is a structural analog of the inhibitory neurotransmitter GABA, and may exert its effects by stimulating of the GABAB receptor subtype. Current studies suggest that baclofen may reduce alcohol dependence. Baclofen is a racemic compound, and its active enantiomer is (R)-Baclofen (l-baclofen or STX209) [B5102]. (The product is for research purpose only.)

References

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