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Levofloxacin
(CAS RN:100986-85-4 Product Number:L0193)

Structure

Levofloxacin

General Information

Product Number L0193

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Purity/Analysis Method >98.0%(HPLC)
Storage Temperature
M.F. / M.W. C18H20FN3O4=361.37
CAS RN 100986-85-4
Related CAS RN
MDL Number MFCD00865049
Packaging and Container
  • Product Details
  • Safety & Regulations

Specification

Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 96.0 %
Melting point 222.0 to 230.0 deg-C
Specific rotation [a]20/D -63.0 to -70.0 deg(C=5, CHCl3)

References

Reaxys-RN 5385660
PubChem SID 87558890
Merck Index(14) 6771
RTECS# UU8815550

GHS

Pictogram
Signal Word Warning
Hazard Statements
  • H302
  • :Harmful if swallowed.
Precautionary Statements
  • P264
  • :Wash hands and face thoroughly after handling.
  • P270
  • :Do not eat, drink or smoke when using this product.
  • P301+P312+P330
  • :IF SWALLOWED: Call a POISON CENTER or doctor if you feel unwell. Rinse mouth.
  • P501
  • :Dispose of contents/container through a waste management company authorized by the local government.

Transport Information

HS Number 2934999090

Application

Levofloxacin: The Active (S)-(-)-Enantiomer of Ofloxacin, Fluoroquinolone Antimicrobial

Levofloxacin, a synthetic fluoroquinolone antimicrobial, is the active (S)-(-)-enantiomer of the racemic drug substance ofloxacin [O0403]. Levofloxacin has broad-spectrum bactericidal activity against most Gram-negative bacteria, many Gram-positive bacteria and some anaerobes. The mechanism of action of ofloxacin (and other fluoroquinolone) involves inhibition of bacterial topoisomerase IV and DNA gyrase (topoisomerases II), enzymes required for DNA replication, transcription, repair and recombination. (The product is for research purpose only.)

References

PubMed Literature

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