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Mirtazapine
(CAS RN:85650-52-8 Product Number:M2151)

Structure

Mirtazapine
Synonym 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepine

General Information

Product Number M2151

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Purity/Analysis Method >98.0%(HPLC)
Storage Temperature
M.F. / M.W. C17H19N3=265.36
CAS RN 85650-52-8
Related CAS RN
MDL Number MFCD00865427
Packaging and Container
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Specification

Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 95.0 %
Melting point 119.0 to 123.0 deg-C

References

Reaxys-RN 549345
PubChem SID 125307817
RTECS# UQ4410250
EC Number 288-060-6

Transport Information

HS Number 2933998090

Application

Mirtazapine: A Noradrenergic and Specific Serotonergic Antidepressant (NaSSA)

Mirtazapine (Org 3770) is the first noradrenergic and specific serotonergic antidepressant (NaSSA). Studies have suggested that mirtazapine acts as an antagonist at central presynaptic α2 adrenergic inhibitory autoreceptors and heteroreceptors, as well as by blocking 5-HT2 and 5-HT3 receptors. Therefore, these antagonisms enhance the release of noradrenaline and 5-HT1A-mediated serotonergic transmission in brain. Mirtazapine is mainly metabolized by CYP1A2, CYP2D6, and CYP3A4. (The product is for research purpose only.)

References

PubMed Literature

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