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(CAS RN:21829-25-4 Product Number:N0528)


Synonym 1,4-Dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic Acid Dimethyl Ester

General Information

Product Number N0528

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Purity/Analysis Method >98.0%(HPLC)(E)
Storage Temperature
M.F. / M.W. C17H18N2O6=346.34
CAS RN 21829-25-4
Related CAS RN
MDL Number MFCD00057326
Packaging and Container
  • Product Details
  • Safety & Regulations


Appearance Light yellow to Yellow to Orange powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(UV-vis method) min. 98.0 %
Melting point 172.0 to 175.0 deg-C
Solubility in Acetone almost transparency


Reaxys-RN 497773
PubChem SID 87573853
Merck Index(14) 6528
RTECS# US7975000
EC Number 244-598-3


Signal Word Warning
Hazard Statements
  • H302
  • :Harmful if swallowed.
Precautionary Statements
  • P264
  • :Wash hands and face thoroughly after handling.
  • P270
  • :Do not eat, drink or smoke when using this product.
  • P301+P312+P330
  • :IF SWALLOWED: Call a POISON CENTER or doctor if you feel unwell. Rinse mouth.
  • P501
  • :Dispose of contents/container through a waste management company authorized by the local government.

Transport Information

HS Number 2933399990


Nifedipine: A Short-Acting Dihydropyridine Calcium Antagonist

Nifedipine is a short-acting dihydropyridine calcium antagonist. It selectively inhibits the transmembrane influx of calcium ions into cardiac and vascular smooth muscle without altering serum calcium concentrations, and induces a relaxation of the muscle. Because of the dilation of resistance vessels, blood pressure falls. Nifedipine is almost completely metabolized by cytochrome P450 3A4 (CYP3A4) in the liver. Nifedipine is a poorly water soluble agent and rapidly metabolized resulting in decreased bioavailability, and then the short-acting can provide increased the risk of stroke et al. Therefore, nifedipine slow-release formulations have been developed. (The product is for research purpose only.)


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