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Resiquimod
(CAS RN:144875-48-9 Product Number:R0197)

Structure

Resiquimod
Synonym 1-[4-Amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol

General Information

Product Number R0197

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Purity/Analysis Method >98.0%(HPLC)
Storage Temperature -20°C
M.F. / M.W. C17H22N4O2=314.39
CAS RN 144875-48-9
Related CAS RN
MDL Number MFCD00937759
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Specification

Purity(HPLC) min. 98.0 area%
Elemental analysis(Nitrogen) 17.00 to 18.50 %

Data of Reference

mp 193°C(lit.)
λmax 325(lit.)

References

Reaxys-RN 9792901
PubChem SID 354335079
Merck Index(14) 8151
RTECS# NJ5911320

Transport Information

HS Number 2933998090

Application

Resiquimod: A Toll-Like Receptor Agonist

Resiquimod (R-848) is a tricyclic imidazoquinolone compound and an imiquimod [I0747] analog. Toll-like receptors (TLRs) play an important role in the innate immune response to pathogens. Reportedly, resiquimod act as an immunomodulator and an anti-viral agent through activation immune cells via the Toll-like receptor 7 and 7/8 (TLR7 and TLR7/8) dependent signaling pathway. And then, resiquimod induces mRNA encoding cytokines including interferon-α (INF-α) at the treatment site. (The product is for research purpose only.)

References

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