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Ursodeoxycholic Acid
(CAS RN:128-13-2 Product Number:U0030)

Structure

Ursodeoxycholic Acid
Synonym 5β-Cholanic Acid-3α,7β-diol
Synonym 3α,7β-Dihydroxy-5β-cholanic Acid

General Information

Product Number U0030

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Purity/Analysis Method >98.0%(T)
Storage Temperature
M.F. / M.W. C24H40O4=392.58
CAS RN 128-13-2
Related CAS RN
MDL Number MFCD00003680
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Specification

Purity(Neutralization titration) min. 98.0 %(after drying)
Melting point 200.0 to 205.0 deg-C
Specific rotation [a]20/D + 59.0 to + 62.0 deg(C=4, EtOH)
Solubility in EtOH almost transparency
Drying loss max. 1.0 %

References

Beilstein 10(3)1635
Reaxys-RN 3219888
PubChem SID 87577760
Merck Index(14) 9889
RTECS# FZ2000000
EC Number 204-879-3

Transport Information

HS Number 2918199890

Application

Ursodeoxycholic Acid: A Secondary Bile Acid with Promoting the Flow of Bile

Ursodeoxycholic acid (ursodiol or UDCA) is a main active compound of bile bear which has been widely used in traditional Chinese medicine for the purpose of promoting the flow of bile (choleretic effect). It is a secondary bile acid resulting from bacterial actions in the colon, and is normally present as a minor fraction of the total bile acids in humans. However, it alters bile acid composition, resulting in decreases in the concentration of the more hydrophobic and cytotoxic bile acids. Furthermore, some studies have suggested that ursodeoxycholic acid protects hepatocytes against bile acid-induced apoptosis. Recently, ursodeoxycholic acid is increasingly used for the treatment of cholestatic liver diseases. (The product is for research purpose only.)

References

PubMed Literature

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