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Brefeldin A
(CAS RN:20350-15-6 Product Number:B3820)


Brefeldin A
Synonym Ascotoxin
Synonym Cyanein
Synonym Decumbin
Synonym γ,4-Dihydroxy-2-(6-hydroxy-1-heptenyl)-4-cyclopentanecrotonic Acid λ-Lactone

General Information

Product Number B3820

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Purity/Analysis Method >98.0%(HPLC)
Storage Temperature <0°C
M.F. / M.W. C16H24O4=280.36
CAS RN 20350-15-6
Related CAS RN
MDL Number MFCD12913297
Packaging and Container
  • Product Details
  • Safety & Regulations


Appearance White to Almost white powder to crystal
Purity(HPLC)(CAD) min. 98.0 area%
Elemental analysis(Carbon) 65.50 to 71.50 %

Data of Reference

mp 204°C(lit.)
[α]20D 93° (C=2,MeOH)(lit.)
λmax 215(EtOH)(lit.)


Reaxys-RN 25191
Merck Index(14) 1369
RTECS# GY8410000


Signal Word Danger
Hazard Statements
  • H301
  • :Toxic if swallowed.
Precautionary Statements
  • P264
  • :Wash hands and face thoroughly after handling.
  • P270
  • :Do not eat, drink or smoke when using this product.
  • P301+P310+P330
  • :IF SWALLOWED: Immediately call a POISON CENTER or doctor. Rinse mouth.
  • P405
  • :Store locked up.
  • P501
  • :Dispose of contents/container through a waste management company authorized by the local government.

Transport Information

UN Number 2811
Class 6.1
Packing Group III
HS Number 2932209090


Brefeldin A: A Macrolide Lactone Antibiotic used as an Inhibitor of Protein Trafficking and Secretion

Brefeldin A (BFA) is a natural fungal macrolide lactone antibiotic. Studies has demonstrated that BFA reversibly interferes with protein trafficking and secretion mediated by the Golgi apparatus and endoplasmic reticulum. Therefore, BFA has been used as a tool to inhibit protein secretion and study the secretory pathway, effects of BFA on Golgi apparatus and other subcellular systems.


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