Home >   Products   >  Advanced Search

Brefeldin A
(CAS RN:20350-15-6 Product Number:B3820)

Structure

Brefeldin A
Synonym Ascotoxin
Synonym Cyanein
Synonym Decumbin
Synonym γ,4-Dihydroxy-2-(6-hydroxy-1-heptenyl)-4-cyclopentanecrotonic Acid λ-Lactone

General Information

Product Number B3820

* Items available from stock in Japan will be delivered in 10 business days.
* Please contact us if you need further information.
(Sales Dept Tel: +32 (0)3 735 07 00 E-mail: Sales-EU@TCIchemicals.com)
* To send your quote request for bulk quantities, please click on the “Request Bulk Quotation” button. Please note that for some of our products we cannot offer bulk quantities.
* TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.

Purity/Analysis Method >98.0%(HPLC)
Storage Temperature <0°C
M.F. / M.W. C16H24O4=280.36
CAS RN 20350-15-6
Related CAS RN
MDL Number MFCD12913297
Packaging and Container
  • Product Details
  • Safety & Regulations

Specification

Purity(HPLC)(CAD) min. 98.0 area%
Elemental analysis(Carbon) 65.50 to 71.50 %

Data of Reference

mp 204°C(lit.)
[α]20D 93° (C=2,MeOH)(lit.)
λmax 215(EtOH)(lit.)

References

Reaxys-RN 25191
Merck Index(14) 1369
RTECS# GY8410000

GHS

Pictogram
Signal Word Danger
Hazard Statements
  • H301
  • :Toxic if swallowed.
Precautionary Statements
  • P264
  • :Wash hands and face thoroughly after handling.
  • P270
  • :Do not eat, drink or smoke when using this product.
  • P301+P310+P330
  • :IF SWALLOWED: Immediately call a POISON CENTER or doctor. Rinse mouth.
  • P405
  • :Store locked up.
  • P501
  • :Dispose of contents/container through a waste management company authorized by the local government.

Transport Information

UN Number 2811
Class 6.1
Packing Group III
HS Number 2932209090

Application

Brefeldin A: A Macrolide Lactone Antibiotic used as an Inhibitor of Protein Trafficking and Secretion

Brefeldin A (BFA) is a natural fungal macrolide lactone antibiotic. Studies has demonstrated that BFA reversibly interferes with protein trafficking and secretion mediated by the Golgi apparatus and endoplasmic reticulum. Therefore, BFA has been used as a tool to inhibit protein secretion and study the secretory pathway, effects of BFA on Golgi apparatus and other subcellular systems.

References

Page Top