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Chlorpromazine Hydrochloride
(CAS RN:69-09-0 Product Number:C2481)

Structure

Chlorpromazine Hydrochloride
Synonym 2-Chloro-10-[3-(dimethylamino)-1-propyl]phenothiazine Hydrochloride

General Information

Product Number C2481

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Purity/Analysis Method >98.0%(HPLC)(T)
Storage Temperature
M.F. / M.W. C17H19ClN2S·HCl=355.32
CAS RN 69-09-0
Related CAS RN 50-53-3
MDL Number MFCD00012654
Packaging and Container
  • Product Details
  • Safety & Regulations

Specification

Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 98.0 %
Melting point 195.0 to 199.0 deg-C

References

Reaxys-RN 3779989
PubChem SID 125307954
Merck Index(14) 2185
RTECS# SO1750000
EC Number 200-701-3

GHS

Pictogram
Signal Word Danger
Hazard Statements
  • H301
  • :Toxic if swallowed.
  • H330
  • :Fatal if inhaled.
Precautionary Statements
  • P260
  • :Do not breathe dust, fume, mist, vapours or spray.
  • P270
  • :Do not eat, drink or smoke when using this product.
  • P284
  • :Wear respiratory protection.
  • P301+P310+P330
  • :IF SWALLOWED: Immediately call a POISON CENTER or doctor. Rinse mouth.
  • P304+P340+P310
  • :IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER or doctor.
  • P403+P233
  • :Store in a well-ventilated place. Keep container tightly closed.

Transport Information

UN Number 2811
Class 6.1
Packing Group I
HS Number 2934309090

Application

Chlorpromazine Hydrochloride: A Dopamine Inhibitor with Antipsychotic Activity

Chlorpromazine hydrochloride is a phenothiazine antipsychotic agent. The precise mechanism of actions is not fully understood. However, chlorpromazine works as a dopamine inhibitor, and the antagonism central dopaminergic function may be related to the therapeutic effect in psychotic conditions. Chlorpromazine can also produce α-adrenergic receptor antagonist action which may produce hypotension. Besides, it is reported that UV irradiation of chlorpromazine produces reactive free radicals which have DNA damaging properties. (The product is for research purpose only.)

References

PubMed Literature

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