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Iguratimod
(CAS RN:123663-49-0 Product Number:I0945)

Structure

Iguratimod
Synonym N-(3-Formamido-4-oxo-6-phenoxy-4H-chromen-7-yl)methanesulfonamide
Synonym N-[7-(Methanesulfonamido)-4-oxo-6-phenoxy-4H-chromen-3-yl]formamide

General Information

Product Number I0945

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Purity/Analysis Method >98.0%(HPLC)(T)
Storage Temperature
M.F. / M.W. C17H14N2O6S=374.37
CAS RN 123663-49-0
Related CAS RN
MDL Number MFCD00882374
Packaging and Container
  • Product Details
  • Safety & Regulations

Specification

Purity(HPLC) min. 98.0 area%
Purity(Neutralization titration) min. 98.0 %
Melting point 238.0 to 242.0 deg-C

References

Reaxys-RN 8640145
PubChem SID 253660421

GHS

Pictogram
Signal Word Warning
Hazard Statements
  • H361fd
  • :Suspected of damaging fertility. Suspected of damaging the unborn child.
Precautionary Statements
  • P201
  • :Obtain special instructions before use.
  • P202
  • :Do not handle until all safety precautions have been read and understood.
  • P280
  • :Wear protective gloves, protective clothing, face protection.
  • P308+P313
  • :IF exposed or concerned: Get medical advice or attention.
  • P405
  • :Store locked up.
  • P501
  • :Dispose of contents/container through a waste management company authorized by the local government.

Transport Information

HS Number 2935909099

Application

Iguratimod (T-614): An Agent with Anti-Inflammatory and Immunomodulatory Activities

Iguratimod (T-614) is an agent with anti-inflammatory and immunomodulatory activities. Iguratimod inhibits the production of immune globulin and inflammatory cytokines such as TNF-α, IL-1β and IL-6 in vitro. Even though the mechanism of action of iguratimod is still not fully understood, the suppression of nuclear factor kappa B (NF-κB) activation has been indicated. Iguratimod is used as a disease modifying anti-rheumatic drug (DMARD). (The product is for research purpose only.)

References

PubMed Literature

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