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Levocetirizine Dihydrochloride
(CAS RN:130018-87-0 Product Number:L0264)

Structure

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Levocetirizine Dihydrochloride
Synonym 2-[2-[4-[(R)-(4-Chlorophenyl)phenylmethyl]piperazin-1-yl]ethoxy]acetic Acid Dihydrochloride

General Information

Product Number L0264

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Purity/Analysis Method >98.0%(HPLC)(T)
Storage Temperature
M.F. / M.W. C21H25ClN2O3·2HCl=461.81
CAS RN 130018-87-0
Related CAS RN 130018-77-8
MDL Number MFCD07366507
Packaging and Container
  • Product Details
  • Safety & Regulations

Specification

Appearance White to Almost white powder to crystaline
Purity(HPLC) min. 98.0 area%
Purity(Neutralization titration) min. 98.0 %

References

Reaxys-RN 9455577
PubChem SID 253661576
Merck Index(14) 2022
RTECS# AG0990000

GHS

Pictogram
Signal Word Warning
Hazard Statements
  • H302
  • :Harmful if swallowed.
Precautionary Statements
  • P264
  • :Wash hands and face thoroughly after handling.
  • P270
  • :Do not eat, drink or smoke when using this product.
  • P301+P312+P330
  • :IF SWALLOWED: Call a POISON CENTER or doctor if you feel unwell. Rinse mouth.
  • P501
  • :Dispose of contents/container through a waste management company authorized by the local government.

Transport Information

HS Number 2933599590

Application

Levocetirizine Dihydrochloride: A New Histamine H1 Antagonist with a Superior Affinity for H1 Receptors over Its Racemate, Cetirizine [C2316]

Levocetirizine dihydrochloride is a new second-generation histamine H1 antagonist, developed from cetirizine [C2316]. Chemically, levocetirizine is the active R-enantiomer of cetirizine. Levocetirizine has a superior affinity and selectivity for H1 receptors over racemic cetirizine or the S-enantiomer, and has a favorable pharmacokinetic profile.

References

PubMed Literature

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