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Pyrilamine Maleate
(CAS RN:59-33-6 Product Number:P2369)


Pyrilamine Maleate
Synonym Mepyramine Maleate
Synonym N-(4-Methoxyphenyl)methyl-N',N'-dimethyl-N-(2-pyridinyl)-1,2-ethanediamine Maleate

General Information

Product Number P2369

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Purity/Analysis Method >98.0%(HPLC)(T)
Storage Temperature
M.F. / M.W. C17H23N3O·C4H4O4=401.46
CAS RN 59-33-6
Related CAS RN 91-84-9
MDL Number MFCD00069333
Packaging and Container
  • Product Details
  • Safety & Regulations


Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 %(total of Ion-Pair)
Purity(Nonaqueous Titration) min. 98.0 %
Melting point 100.0 to 104.0 deg-C

Data of Reference

λmax 310(EtOH)(lit.)


Reaxys-RN 3836479
PubChem SID 354333684
Merck Index(14) 7984
RTECS# UT1225000
EC Number 200-422-7


Signal Word Warning
Hazard Statements
  • H302
  • :Harmful if swallowed.
Precautionary Statements
  • P264
  • :Wash hands and face thoroughly after handling.
  • P270
  • :Do not eat, drink or smoke when using this product.
  • P301+P312+P330
  • :IF SWALLOWED: Call a POISON CENTER or doctor if you feel unwell. Rinse mouth.
  • P501
  • :Dispose of contents/container through a waste management company authorized by the local government.

Transport Information

HS Number 2933399990


Pyrilamine Maleate: A First Generation Histamine H1 Receptor Antagonist

Pyrilamine maleate, also known as pyrilamine maleate, is a first generation histamine H1 receptor antagonist. Pyrilamine binds to a G protein-coupled form of the receptor and promotes a G protein-coupled inactive state of the H1 receptor that interferes with the Gq/11-mediated signaling. Pyrilamine permeates the blood-brain barrier causing drowsiness. Pyrilamine also has anticholinergic properties. For reference, we also have related first generation histamine H1 receptor antagonists, such as pheniramine maleate [P2271], chlorpheniramine maleate [C0873] and bromopheniramine maleate [B5167]. (The product is for research purpose only.)


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