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Pemirolast Potassium
(CAS RN:100299-08-9 Product Number:P2547)

Structure

Pemirolast Potassium
Synonym 9-Methyl-3-(1H-tetrazol-5-yl)-4H-pyrido[1,2-a]pyrimidin-4-one Potassium Salt

General Information

Product Number P2547

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Purity/Analysis Method >98.0%(HPLC)(T)
Storage Temperature 0-10°C
M.F. / M.W. C10H7KN6O=266.31
CAS RN 100299-08-9
Related CAS RN 69372-19-6
MDL Number MFCD01690051
Packaging and Container
  • Product Details
  • Safety & Regulations

Specification

Appearance Light yellow to Yellow to Green powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Neutralization titration) min. 98.0 %

Data of Reference

mp 317°C(dec.)(lit.)

References

Reaxys-RN 8097604
PubChem SID 354334415
Merck Index(14) 7078
RTECS# UV1164470

GHS

Pictogram
Signal Word Warning
Hazard Statements
  • H302
  • :Harmful if swallowed.
  • H361fd
  • :Suspected of damaging fertility. Suspected of damaging the unborn child.
  • H362
  • :May cause harm to breast-fed children.
Precautionary Statements
  • P201
  • :Obtain special instructions before use.
  • P260
  • :Do not breathe dusts or mists.
  • P263
  • :Avoid contact during pregnancy/while nursing.
  • P270
  • :Do not eat, drink or smoke when using this product.
  • P280
  • :Wear protective gloves, protective clothing, face protection.
  • P308+P313
  • :IF exposed or concerned: Get medical advice or attention.

Transport Information

HS Number 2933599590

Application

Pemirolast Potassium: A Water-Soluble Inhibitor of Type I Allergy

Pemirolast potassium is a water-soluble inhibitor of type I allergy. Pharmacological studies indicate that it suppresses the formation of 1,2-diacylglycerol and phosphatidic acid, and the decrease in phosphatidylinositol (PI). It also can stabilize the cell membrane of mast cells, inhibit the inflow and release of Ca2+, inhibit the activation of phosphodiesterase and increase the intracellular cAMP levels. Recently, some laboratory animal studies reported that it can reduce chemotherapy-induced nausea and vomiting. (The product is for research purpose only.)

References

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