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Bilastine
(CAS RN:202189-78-4 Product Number:B5392)

Structure

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Bilastine
Synonym 2-[4-[2-[4-[1-(2-Ethoxyethyl)-1H-benzo[d]imidazol-2-yl]piperidin-1-yl]ethyl]phenyl]-2-methylpropanoic Acid

General Information

Product Number B5392

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Purity/Analysis Method >98.0%(HPLC)(T)
Storage Temperature
M.F. / M.W. C28H37N3O3=463.62
CAS RN 202189-78-4
Related CAS RN
MDL Number MFCD09837814
Packaging and Container
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Specification

Purity(HPLC) min. 98.0 area%
Purity(Neutralization titration) min. 98.0 %
Melting point 200.0 to 204.0 deg-C

References

Reaxys-RN 13851185
PubChem SID 354335500

Transport Information

HS Number 2933998090

Application

Bilastine: A Selective Histamine H1 Receptor Antagonist

Bilastine is a selective histamine H1 receptor antagonist. On the other hand, the results of studies on bilastine confirmed the lack of significant antagonism against not only histamine H2 and H3 receptors but also serotonin, bradykinin, leukotriene D4, calcium, muscarinic M3-receptors, α1-adrenoceptors, and β2-adrenoceptors. Furthermore, bilastine do not cause sedation or interact with cytochrome P 450. Therefore, bilastine is used as a second generation H1-antihistamine for the treatment of allergic rhinitis and chronic urticarial. (The product is for research purpose only.)

References

PubMed Literature

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