Home >   Products   >  Advanced Search

Clemizole Hydrochloride
(CAS RN:1163-36-6 Product Number:C3468)

Structure

Clemizole Hydrochloride
Synonym 1-(4-Chlorobenzyl)-2-(pyrrolidin-1-ylmethyl)benzimidazole Hydrochloride

General Information

Product Number C3468

* Items available from stock in Japan will be delivered in 10 business days.
* Please contact us if you need further information.
(Sales Dept Tel: +32 (0)3 735 07 00 E-mail: Sales-EU@TCIchemicals.com)
* To send your quote request for bulk quantities, please click on the “Request Bulk Quotation” button. Please note that for some of our products we cannot offer bulk quantities.
* TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.

Purity/Analysis Method >98.0%(HPLC)
Storage Temperature 0-10°C
M.F. / M.W. C19H20ClN3·HCl=362.30
CAS RN 1163-36-6
Related CAS RN 442-52-4
MDL Number MFCD00051435
Packaging and Container
  • Product Details
  • Safety & Regulations

Specification

Purity(HPLC) min. 98.0 area%
Elemental analysis(Nitrogen) 11.00 to 12.00 %

Data of Reference

mp 241°C(lit.)

References

Reaxys-RN 3791565
PubChem SID 354335133
Merck Index(14) 2346
RTECS# DD6730000
EC Number 214-605-4

GHS

Pictogram
Signal Word Warning
Hazard Statements
  • H302
  • :Harmful if swallowed.
Precautionary Statements
  • P264
  • :Wash hands and face thoroughly after handling.
  • P270
  • :Do not eat, drink or smoke when using this product.
  • P301+P312+P330
  • :IF SWALLOWED: Call a POISON CENTER or doctor if you feel unwell. Rinse mouth.
  • P501
  • :Dispose of contents/container through a waste management company authorized by the local government.

Transport Information

HS Number 2933998090

Application

Clemizole Hydrochloride: A Histamine H1 Receptor Antagonist with Anti-Virus and Various Effects

Clemizole hydrochloride is a histamine H1 receptor antagonist1). Recently, it is reported that clemizole inhibits hepatitis C virus (HCV) replication2), and also potently inhibits transient receptor potential channel 5 (TRPC5).3) In addition, clemizole reportedly can be used for the treatment of Dravet syndrome which is often caused by Scn1a mutations, a voltage-gated sodium channel.4) (The product is for research purpose only.)

References

PubMed Literature

Page Top