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Acylation Reagents [Protecting Reagents]

 Acyl protecting groups are used for the protection of hydroxy groups and amino groups. Acetyl (Ac), benzoyl (Bz), and pivaloyl (Piv) groups are commonly used. Pivaloyl group can selectively protect less sterically-hindered hydroxy groups due to its steric-hindrance. Generally, it is stable under acidic conditions and oxidative conditions. Acyl protecting groups are deprotected under basic conditions or reductive conditions (DIBAL, LAH, etc.).

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