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N,O-Bis(trimethylsilyl)acetamide
(CAS RN:10416-59-8 Product Number:B0511)

Structure

N,O-Bis(trimethylsilyl)acetamide
Synonym BSA

General Information

Product Number B0511

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Purity/Analysis Method >80.0%(GC)
Storage Temperature
M.F. / M.W. C8H21NOSi2=203.43
CAS RN 10416-59-8
Related CAS RN
MDL Number MFCD00008270
Packaging and Container 10mL-Vial, (View image) 100mL-Vial (View image)
  • Product Details
  • Safety & Regulations

Specification

Purity(GC) min. 80.0 %
Refractive index n20/D 1.4140 to 1.4180
Effect test of TMS derivatization Effective as derivatization agent DL-Threonine

Data of Reference

flp 42°C(lit.)
bp 73°C/35mmHg(lit.)

References

Reaxys-RN 1306669
PubChem SID 87563535
F&F 3,23
RTECS# AK3000000
EC Number 233-892-7

GHS

Pictogram
Signal Word Danger
Hazard Statements
  • H226
  • :Flammable liquid and vapour.
  • H302
  • :Harmful if swallowed.
  • H314
  • :Causes severe skin burns and eye damage.
Precautionary Statements
  • P260
  • :Do not breathe dusts or mists.
  • P280
  • :Wear protective gloves, protective clothing, face protection.
  • P301+P330+P331+P310
  • :IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Immediately call a POISON CENTER or doctor.
  • P303+P361+P353+P310+P363
  • :IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water or shower. Immediately call a POISON CENTER or doctor. Wash contaminated clothing before reuse.
  • P304+P340+P310
  • :IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER or doctor.
  • P305+P351+P338+P310
  • :IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor.

Transport Information

UN Number 2920
Class 8/3
Packing Group II
HS Number 2931399090

Application

Trimethylsilylating Reagent for GC Derivatization

B0511, B0911

Experimental procedure:
BSA is added to a sample (10-50 mg) placed into a dry vessel, and the vessel is sealed tightly. If necessary, it is heated at 70-80 °C for 30 min - 1 h.

References

Reactivity of Trimethylsilylating Reagents : Trimethylsilylation of Alcohols

B0511, B0510, B0911, T0691

References

  • Protection for the Hydroxyl Group, Including 1,2- and 1,3-Diols
    • P. G. M. Wuts, in Greene’s Protective Groups in Organic Synthesis, 5th ed., ed. by P. G. M. Wuts, John Wiley & Sons, Inc., Hoboken, New Jersey, 2014, Chap. 2, 17.

PubMed Literature

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