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SB 216763
(CAS RN:280744-09-4 Product Number:B5716)


SB 216763
Synonym 3-(2,4-Dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione

General Information

Product Number B5716

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Purity/Analysis Method >98.0%(HPLC)
Storage Temperature <0°C
M.F. / M.W. C19H12Cl2N2O2=371.22
CAS RN 280744-09-4
Related CAS RN
MDL Number MFCD09753369
Packaging and Container
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Purity(HPLC) min. 98.0 area%

Data of Reference

mp 104°C(lit.)


Reaxys-RN 11333014
PubChem SID 354335732

Transport Information

HS Number 2933998090


SB 216763: An ATP-Competitive Inhibitor of GSK-3α

SB 216763 is reportedly an ATP-competitive inhibitor of glycogen synthase kinase-3α (GSK-3α) in vitro with an IC50 value of 34 nM. GSK-3 is a serine/threonine protein kinase, and inhibition of its activity has been proposed to play a role in the regulation of numerous signalling pathways that elicit cellular responses.


PubMed Literature

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