Home >   Products   >  Advanced Search

1-[2-(Trimethylsilyl)ethoxycarbonyloxy]benzotriazole
(CAS RN:113306-55-1 Product Number:T2590)

Structure

1-[2-(Trimethylsilyl)ethoxycarbonyloxy]benzotriazole
Synonym Teoc-OBt

General Information

Product Number T2590

* Items available from stock in Japan will be delivered in 10 business days.
* Please contact us if you need further information.
(Sales Dept Tel: +32 (0)3 735 07 00 E-mail: Sales-EU@TCIchemicals.com)
* To send your quote request for bulk quantities, please click on the “Request Bulk Quotation” button. Please note that for some of our products we cannot offer bulk quantities.
* TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.

Purity/Analysis Method >98.0%(HPLC)
Storage Temperature
M.F. / M.W. C12H17N3O3Si=279.37
CAS RN 113306-55-1
Related CAS RN
MDL Number
Packaging and Container
  • Product Details
  • Safety & Regulations

Specification

Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Elemental analysis(Nitrogen) 14.30 to 15.80 %

References

Reaxys-RN 5081030
PubChem SID 87560905

Transport Information

HS Number 2931399090

Application

Reagents for Introduction of the Teoc-Protecting Group

T2590, T2591

Typical Procedure:
To a stirred suspension of the amino acid (1 mmol) in water (1 mL) is added a solution of triethylamine (0.21 mL, 1.5 mmol) in dioxane (1 mL) followed by Teoc-OBt (0.31 g, 1.1 mmol) or Teoc-OSu (0.29 g, 1.1 mmol). The mixture is stirred at room temperature overnight, then diluted with water (5 mL), acidified with saturated potassium hydrogen sulfate solution, and extracted with diethyl ether (3 × 15 mL). The combined organic layers are washed with water (4 × 20 mL), dried with magnesium sulfate, and evaporated. The resultant Teoc-amino acid is purified by crystallization (if solid) or obtained as their cyclohexylammonium salts (if they are oils).

References

Page Top