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Fidaxomicin
(CAS RN:873857-62-6 Product Number:F1216)

Structure

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Fidaxomicin
Synonym Clostomicin B1
Synonym Lipiarmycin A3
Synonym Tiacumicin B

General Information

Product Number F1216

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Purity/Analysis Method >98.0%(HPLC)
Storage Temperature 0-10°C
M.F. / M.W. C52H74Cl2O18=1058.05
CAS RN 873857-62-6
Related CAS RN
MDL Number MFCD27976367
Packaging and Container
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Specification

Purity(HPLC) min. 98.0 area%
Melting point 159.0 to 163.0 deg-C

Data of Reference

[α]20D -6.9° (C=2,MeOH)(lit.)

References

Reaxys-RN 12687773

Transport Information

HS Number 2941900000

Application

Fidaxomicin: A Narrow-Spectrum Macrolide Antibiotic Active against Clostridia

Fidaxomicin (OPT-80) is a narrow-spectrum macrolide antibiotic obtained from the Actinomycete Dactylosporangium aurantiacum. Fidaxomicin is active primarily against species of clostridia, including Clostridium difficile (or Clostridioides difficile) that is a major cause of hospital-acquired diarrhea and mortality in individuals. Fidaxomicin has demonstrated potent in vitro bactericidal activity, inhibiting RNA synthesis by RNA polymerases, with limited or no activity against normal fecal flora. In addition, it is minimally absorbed from the intestinal tract. (The product is for research purpose only.)

References

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