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SC-560
(CAS RN:188817-13-2 Product Number:C3572)

Structure

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SC-560
Synonym 5-(4-Chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluoromethyl)-1H-pyrazole

General Information

Product Number C3572

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Purity/Analysis Method >98.0%(HPLC)
Grade
Storage Temperature 0-10°C
M.F. / M.W. C17H12ClF3N2O=352.74
CAS RN 188817-13-2
Related CAS RN
MDL Number MFCD02179214
Packaging and Container
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  • Reference & Application

Specification

Purity(HPLC) min. 98.0 area%
Elemental analysis(Nitrogen) 7.50 to 8.50 %
Melting point 61.0 to 65.0 deg-C

References

Reaxys-RN 7719788
RTECS# UQ6457100

Application

SC-560: A Selective Cyclooxygenase-1 (COX-1) Inhibitor

SC-560 is a strucutral analog of celecoxib [C2816] and a member of cyclooxygenase (COX) inhibitors which includes selective COX-2 inhibitors such as celecoxib and rofecoxib [R0206]. However, unlike these selective COX-2 inhibitors, SC-560 is a selective COX-1 inhibitor. Reportedly, SC-560 causes intestinal hypermotility, bacterial invasion, inhibition of prostaglandin E2 synthesis, etc. In addition, SC-560 suppresses cell proliferation and induces apoptosis in cancer cells in the blood. (The product is for research purpose only.)

References

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